We know that in the Macbook with Windows OS will work with the MST, Linux we have not tested yet.
The INTEL HD 5K series supports MST up to 3 independent displays and the 6K series will as well. For Mac OS we have found some issues. I tested the MacBook Pro 15″ 2015 and found that the MST 1-3 will not work properly. This is mainly due to the OS and not the MST Hub.
Hope this helps.