We do not recommend to run both Intel graphics and the AMD Catalyst control center. I will suggest to disable the onboard graphics under the mainboard BIOS and deinstall the intel graphics drivers.
As a matter of precaution, I will suggest to also deinstall the AMD Catalyst driver and reinstall them again. You can use this utility (DDU) once is done to completely remove the drivers and do it in safe mode.
Eyefinity 6 cards can run only two passive adapters and the rest must be active adapters unless you have displayport monitors. Make sure you always reset the display in case you have any issues.