Hi BiggerBoat,
Yes the adapter work with WIN10.
To not exeed bandwidth of 18Gbps (max for HDMI2.0), when chosing a resoltuion fo 3840×2160 at 60Hz the BPC need to be set to 8Bit. This is somthing different than what you are talking about (BPP).
Checklist
* Make sure the HDMI cable you are using can do HDMI2.0 or 18Gbps.
I know it sounds a bit “easy” but many cables do state to support 4K but actually do not support that in 60Hz and/or the full bandwidth, that certainly goes for cables longer than 3 meters. It is always best to go for a certified cable, something like this http://www.club-3d.com/index.php/products/reader.en/product/hdmi-20-high-speed-4k60hz-uhd-cable-.html
* Make sure the HDMI input used on the TV is capable of doing 4K at 60Hz often there are more HDMI inputs, but not always all are HDMI2.0 spec.
* On many TV’s you need to turn on “UHD Color” or “Advanced or Enhanced” setting manually in the settings of your TV for the HDMI port to which your pc is connected.
* Also it could help when connecting 2 screens, to set the screen connected thru the Adapter as second/secondary screen
* I advise you to make a custom resolution, set resolution to 3840×2160 at 60Hz and set Timing standard to CVT-RB (reduced blanking)
* Please make sure you do not have any Displayport Splitter or Hub attached to the Graphics Card.
*Please note that in some cases configurations in SLI and/or Cross-fire might casue issues. Please disable SLI and/or Crossfire if so.
* Color Depth need to be set to 8 bpc (when running 4:4:4).